Description
Product Characteristics:
Aliases: Adenosinetriphosphatase 14k chain antibody, ATP6S14 antibody, ATP6V1F antibody, ATPase, H+ transporting, lysosomal 14 kDa, V1 subunit F antibody, ATPase, vacuolar, 14 kD antibody, H(+)-transporting two-sector ATPase, 14kD subunit antibody, MGC117321 antibody, MGC126037 antibody, MGC126038 antibody, V-ATPase 14 kDa subunit antibody, V-ATPase subunit F antibody, V-type proton ATPase subunit F antibody, Vacuolar ATP synthase subunit F antibody, Vacuolar proton pump subunit F antibody, VATF antibody, VATF_HUMAN antibody, Vma7 antibody
Target Information: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is the V1 domain F subunit protein. [provided by RefSeq, Jul 2008]